Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1

Abstract Organoids are a three-dimensional (3D) culture system that simulate actual organs. Therefore, tumor organoids are expected to predict precise response to chemotherapy in patients. However, to date, few studies have studied the drug responses in organoids of malignant mesothelioma (MM). The...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Fumiya Ito, Katsuhiro Kato, Izumi Yanatori, Yuki Maeda, Toyoaki Murohara, Shinya Toyokuni
Format: Article
Language:English
Published: BMC 2023-05-01
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10966-4