Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case report and literature review

A 5-year-old male child was diagnosed with interdigitating dendritic cell sarcoma (IDCS) during his maintenance therapy for B-cell precursor acute lymphoblastic leukemia (B-ALL). Multiplex lymph node involvements of the neck were found by positron emission tomography CT (PET-CT). Treatments, includi...

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Bibliographic Details

Published in:	Frontiers in Pediatrics
Main Authors:	Alex Jenei, Gábor Bedics, Dániel J. Erdélyi, Judit Müller, Tamás Györke, Csaba Bödör, Ágota Szepesi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Subjects:	interdigitating dendritic cell sarcoma MAP2K1 mutation pediatric sarcoma trans-differentiation secondary malignant histiocytosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2022.959307/full