Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines

Alteration in cholesterol metabolism has been implicated in the pathogenesis of several neurodegenerative disorders. Apolipoprotein E (ApoE) is the major component of brain lipoproteins supporting cholesterol transport. We previously reported that the acute-phase protein Haptoglobin (Hpt) binds ApoE...

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发表在:	Frontiers in Cellular Neuroscience
Main Authors:	Maria Stefania eSpagnuolo, Bernardetta eMaresca, Maria Pina eMollica, Gina eCavaliere, Carolina eCefaliello, Giovanna eTrinchese, Maria Grazia eEsposito, Rosaria eScudiero, Marianna eCrispino, Paolo eAbrescia, Luisa eCigliano
格式:	文件
语言:	英语
出版:	Frontiers Media S.A. 2014-08-01
主题:	Aging Cholesterol rat Apolipoprotein E Haptoglobin human neuroblastoma cell line SH-SY5Y
在线阅读:	http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00212/full