Ancestral Wheat Types Release Fewer Celiac Disease Related T Cell Epitopes than Common Wheat upon Ex Vivo Human Gastrointestinal Digestion

Celiac disease (CeD) is an autoimmune enteropathy triggered by immunogenic gluten peptides released during the gastrointestinal digestion of wheat. Our aim was to identify T cell epitope-containing peptides after ex vivo digestion of ancestral (einkorn, spelt and emmer) and common (hexaploid) wheat...

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Bibliographic Details

Published in:	Foods
Main Authors:	Tora Asledottir, Rashida Rehman, Gianfranco Mamone, Gianluca Picariello, Tove Gulbrandsen Devold, Gerd Elisabeth Vegarud, Arne Røseth, Tor Erling Lea, Trond S. Halstensen, Pasquale Ferranti, Anne Kjersti Uhlen
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Subjects:	Celiac disease wheat ex vivo digestion T cell epitope immunogenic peptide
Online Access:	https://www.mdpi.com/2304-8158/9/9/1173