Identification of radiation-sensitive genes as biomarkers for biodosimetry: an ex vivo analysis of TNFRSF10B, ZMAT3, POLH, and PLK2 in human blood samples

Abstract Background Humans are exposed to ionizing radiation (IR), which causes direct and indirect DNA damage. Biodosimetry is a critical component of clinical care following radiation exposure, enabling accurate assessment and mitigation of health effects. The present study was conducted to invest...

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Bibliographic Details
Published in:BMC Medical Genomics
Main Authors: Mahsa Boogari, Hossein Mozdarani, Aziz Mahmoudzadeh, Amirabbas Ebrahimi
Format: Article
Language:English
Published: BMC 2025-10-01
Subjects:
Online Access:https://doi.org/10.1186/s12920-025-02209-1