Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence.

Telomeres have the ability to adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. There...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Tina Wagner, Lara Pérez-Martínez, René Schellhaas, Marta Barrientos-Moreno, Merve Öztürk, Félix Prado, Falk Butter, Brian Luke
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-12-01
Online Access:	https://doi.org/10.1371/journal.pgen.1008603