VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei

The Trypanosoma (T) brucei life cycle alternates between the tsetse fly vector and the mammalian host. In the insect, T. brucei undergoes several developmental stages until it reaches the salivary gland and differentiates into the metacyclic form, which is capable of infecting the next mammalian hos...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Eliane Tihon, Karinna Rubio-Peña, Annick Dujeancourt-Henry, Aline Crouzols, Brice Rotureau, Lucy Glover
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Subjects:	Trypanosoma brucei VSG antigenic variation monoallelic expression metacyclogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.851475/full