β-Arrestin 2 Promotes Hepatocyte Apoptosis by Inhibiting Akt Pathway in Alcoholic Liver Disease

Alcoholic liver disease (ALD) is a complex process that includes a wide range of hepatic lesions, from steatosis to cirrhosis, and even hepatocellular carcinoma (HCC). Accumulating evidence shows that the cytotoxic effects of ethanol metabolism lead to cell apoptosis and necrosis in ALD. Recently, s...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Ying-Yin Sun, Yu-Xin Zhao, Xiao-Feng Li, Cheng Huang, Xiao-Ming Meng, Jun Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-09-01
Subjects:	alcoholic liver disease (ALD) β-arrestin 2 (Arrb2) hepatocyte apoptosis Akt
Online Access:	https://www.frontiersin.org/article/10.3389/fphar.2018.01031/full