Integrative transcriptomic and metabolomic analysis explores mechanisms by which Astragalus membranaceus and Salvia miltiorrhiza ameliorates hypertensive renal damage

Abstract To explore the mechanism by which Astragalus membranaceus and Salvia miltiorrhiza (AS) regulates the “metabolic- transcriptional” co-expression network to improve Hypertensive renal damage (HRD). Spontaneously hypertensive rats (SHRs) were used to establish the model of HRD. The structure a...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Wenpeng Liu, Cong Han, Wanli Xu, Yanyun Jiang, Yao Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-09-01
Subjects:
Metabolomics
Transcriptomic
Hypertensive renal damage
Astragalus membranaceus
Salvia miltiorrhiza
Mechanism
Online Access:https://doi.org/10.1038/s41598-025-18241-1

Internet

https://doi.org/10.1038/s41598-025-18241-1

Similar Items