Long-term treatment with metformin in the prevention of fatty liver in Zucker diabetic fatty rats

Abstract Background Treatment with metformin, the biguanide of hepatic insulin sensitizer, in patients with non-alcoholic fatty liver disease (NAFLD) has been reported with contradictory findings regarding the effectiveness on blood lipids and liver histology. In this study, we aimed to explore the...

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Bibliographic Details

Published in:	Diabetology & Metabolic Syndrome
Main Authors:	Yi Sui, Xianhe Kong, Rongrong Fan, Yanbin Ye, Haiyan Mai, Shuyu Zhuo, Wei Lu, Peishan Ruan, Shi Fang, Tao Yang
Format:	Article
Language:	English
Published:	BMC 2019-11-01
Subjects:	Metformin Non-alcoholic fatty liver disease Zucker diabetic fatty rats Gene expression profiling
Online Access:	http://link.springer.com/article/10.1186/s13098-019-0491-1