Sex and Age-Based Differences in Immune Responses to a Peptide Vaccine for Melanoma in Two Clinical Trials

Objectives: Little is known about the impact of patient age and biological sex on immune responses to melanoma vaccines, especially CD4⁺ T cell immune responses to peptides presented by Class II MHC molecules. Methods: We assessed the impact of age and sex on CD4+ T cell and a...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Serena M. Vilasi, Craig L. Slingluff
Format:	Article
Language:	English
Published:	MDPI AG 2025-02-01
Subjects:	melanoma vaccine peptide vaccine T cell response patient sex patient age
Online Access:	https://www.mdpi.com/2076-393X/13/2/194