An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors

Cancer research: Mathematical model describes mechanics of cell coordination In many cancers, spreading and the formation of metastasis involve the coordinated migration of many cells. An interdisciplinary team of researchers from Heidelberg and Frankfurt studied the collective movement of cultured...

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Bibliographic Details
Published in:npj Systems Biology and Applications
Main Authors: Damian Stichel, Alistair M. Middleton, Benedikt F. Müller, Sofia Depner, Ursula Klingmüller, Kai Breuhahn, Franziska Matthäus
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Online Access:https://doi.org/10.1038/s41540-017-0006-3