Dapagliflozin added to metformin reduces perirenal fat layer in type 2 diabetic patients with obesity

Abstract Sodium-glucose co-transporters type 2 inhibitors (SLGT2i) are highly effective in controlling type 2 diabetes, but reported beneficial cardiovascular effects suggest broader actions on insulin resistance. Weight loss may be initially explained by glycosuria-induced net caloric output and se...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Guillem Cuatrecasas, Francisco De Cabo, M. José Coves, Ioana Patrascioiu, Gerardo Aguilar, Gabriel Cuatrecasas, Sonia March, Marta Calbo, Olga Rossell, Mariona Balfegó, Camila Benito, Silvana Di Gregorio, Pilar Garcia Lorda, Elena Muñoz
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-05-01
Subjects:	Ultrasound Dapaglifozin Metformin Preperitoneal fat Omental fat Perirenal fat
Online Access:	https://doi.org/10.1038/s41598-024-61590-6