Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes

Striated skeletal muscle cells from humans represent a valuable source for in vitro studies of the motoric system as well as for pathophysiological investigations in the clinical settings. Myoblasts can readily be grown from human muscle tissue. However, if muscle tissue is unavailable, myogenic cel...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Stem Cell Research
المؤلفون الرئيسيون:	M. Demestre, M. Orth, K.J. Föhr, K. Achberger, A.C. Ludolph, S. Liebau, T.M. Boeckers
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2015-09-01
الموضوعات:	Human induced pluripotent stem cells Myotubes Neuromuscular junction Motoneuron Motoneuron diseases Acetylcholine receptor Amyotrophic lateral sclerosis
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S1873506115001026