Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Antimicrobial resistance in the sexually transmitted bacterium Neisseria gonorrhoeae is compromising the management and control of gonorrhea globally. Optimized use and enhanced stewardship of current antimicrobials and development of novel antimicrobials are imperative. The first in class zolifloda...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Susanne Jacobsson, Daniel Golparian, Joakim Oxelbark, Fabian Y. S. Kong, Renata Maria Augusto Da Costa, Francois Franceschi, David Brown, Arnold Louie, George Drusano, Magnus Unemo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	Neisseria gonorrhoeae hollow-fiber infection model zoliflodacin doxycycline pharmacodynamics antimicrobial treatment
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1291885/full