Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice

Nootkatone (NKT), a major ingredient of Alpinia oxyphylla, exhibited potential nephroprotective effects; however, the precise molecular mechanisms remain poorly understood. This study aimed to study the nephroprotective effects of NKT and the underlying mechanisms in a mouse model. Our results showe...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Chongshan Dai, Mingchao Liu, Qinzhi Zhang, Subhajit Das Gupta, Shusheng Tang, Jianzhong Shen
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	nootkatone oxidative stress nephrotoxicity Nrf2/HO-1 pathway NF-κB pathway
Online Access:	https://www.mdpi.com/2076-3921/12/2/370