Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

Abstract Background Chronic kidney disease (CKD) involves a variety of pathological processes, and ferroptosis plays a vital role in CKD progression. Targeting ferroptosis is a promising strategy for the treatment of CKD. However, inhibitors of ferroptosis have not been used in the clinical treatmen...

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Bibliographic Details
Published in:Molecular Medicine
Main Authors: Jiayu Song, Hongri Wang, Jingyi Sheng, Wen Zhang, Juan Lei, Weihua Gan, Fangfang Cai, Yunwen Yang
Format: Article
Language:English
Published: BMC 2023-10-01
Subjects:
Vitexin
Ferroptosis
CKD
NRF2
Antioxidant
Online Access:https://doi.org/10.1186/s10020-023-00735-1

Internet

https://doi.org/10.1186/s10020-023-00735-1

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