In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

Abstract TDP-43 proteinopathies are a heterogeneous group of neurodegenerative disorders that share the presence of aberrant, misfolded and mislocalized deposits of the protein TDP-43, as in the case of amyotrophic lateral sclerosis and some, but not all, pathological variants of frontotemporal deme...

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Bibliographic Details

Published in:	Translational Neurodegeneration
Main Authors:	Juan I. López-Carbonero, Irene García-Toledo, Laura Fernández-Hernández, Pablo Bascuñana, María J. Gil-Moreno, Jordi A. Matías-Guiu, Silvia Corrochano
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	TDP-43 proteinopathy Biomarkers Early diagnosis ALS FTD LATE
Online Access:	https://doi.org/10.1186/s40035-024-00419-8