Imputation-Aware Tag SNP Selection To Improve Power for Large-Scale, Multi-ethnic Association Studies

The emergence of very large cohorts in genomic research has facilitated a focus on genotype-imputation strategies to power rare variant association. These strategies have benefited from improvements in imputation methods and association tests, however little attention has been paid to ways in which...

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Bibliographic Details

Published in:	G3: Genes, Genomes, Genetics
Main Authors:	Genevieve L. Wojcik, Christian Fuchsberger, Daniel Taliun, Ryan Welch, Alicia R Martin, Suyash Shringarpure, Christopher S. Carlson, Goncalo Abecasis, Hyun Min Kang, Michael Boehnke, Carlos D. Bustamante, Christopher R. Gignoux, Eimear E. Kenny
Format:	Article
Language:	English
Published:	Oxford University Press 2018-10-01
Subjects:	Genomics Statistical Genetics Imputation tag SNPs array design
Online Access:	http://g3journal.org/lookup/doi/10.1534/g3.118.200502