Pathological Relevance of Anti-Hsp70 IgG Autoantibodies in Epidermolysis Bullosa Acquisita

Stress-induced heat shock protein 70 (Hsp70) is a key intra- and extracellular molecular chaperone implicated in autoimmune processes. Highly immunogenic extracellular Hsp70 can activate innate and acquired (adaptive) immune responses driving the generation of anti-Hsp70 autoantibodies that are freq...

詳細記述

書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Stefan Tukaj, Jagoda Mantej, Krzysztof Sitko, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Michael Kasperkiewicz
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2022-04-01
主題:	autoimmune bullous diseases (AIBDs) epidermolysis bullosa acquisita (EBA) heat shock proteins (Hsps) Hsp70 autoantibodies nuclear factor kappa B (NF-κB)
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.877958/full