Mito-priming as a method to engineer Bcl-2 addiction
Apoptosis often requires mitochondrial outer membrane permeabilization, a process targeted by Bcl-2-binding BH3 mimetics. Here the authors describe and apply 'mito-priming', a method that allows triggering mitochondrial apoptosis in a synchronous manner, facilitating the investigation of m...
| الحاوية / القاعدة: | Nature Communications |
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| المؤلفون الرئيسيون: | , , , , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Nature Portfolio
2016-02-01
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| الوصول للمادة أونلاين: | https://doi.org/10.1038/ncomms10538 |