Mito-priming as a method to engineer Bcl-2 addiction
Apoptosis often requires mitochondrial outer membrane permeabilization, a process targeted by Bcl-2-binding BH3 mimetics. Here the authors describe and apply 'mito-priming', a method that allows triggering mitochondrial apoptosis in a synchronous manner, facilitating the investigation of m...
全面介紹
書目詳細資料
| 發表在: | Nature Communications |
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| Main Authors: |
Jonathan Lopez,
Margaux Bessou,
Joel S. Riley,
Evangelos Giampazolias,
Franziska Todt,
Tony Rochegüe,
Andrew Oberst,
Douglas R. Green,
Frank Edlich,
Gabriel Ichim,
Stephen W. G. Tait |
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| 格式: | Article
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| 語言: | 英语 |
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| 出版: |
Nature Portfolio
2016-02-01
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| 在線閱讀: | https://doi.org/10.1038/ncomms10538
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