The penicillin binding protein 1A of Helicobacter pylori, its amoxicillin binding site and access routes

Abstract Background Amoxicillin-resistant H. pylori strains are increasing worldwide. To explore the potential resistance mechanisms involved, the 3D structure modeling and access tunnel prediction for penicillin-binding proteins (PBP1A) was performed, based on the Streptococcus pneumoniae, PBP 3D s...

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Bibliographic Details

Published in:	Gut Pathogens
Main Authors:	Bahareh Attaran, Najmeh Salehi, Bahareh Ghadiri, Maryam Esmaeili, Shadi Kalateh, Mohammad Tashakoripour, Mahmoud Eshagh Hosseini, Marjan Mohammadi
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Subjects:	H. pylori Amoxicillin Resistant PBP1A S414R V469M
Online Access:	https://doi.org/10.1186/s13099-021-00438-0