Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

Abstract Background Neuroinflammation is a crucial factor in the development of secondary brain injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers strong neuroprotective effects in experimental ischemic stroke. However, whether this myokine can exert neuro...

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Bibliographic Details
Published in:Journal of Neuroinflammation
Main Authors: Yao Wang, Mi Tian, Jiaying Tan, Xu Pei, Chaocheng Lu, Yuewen Xin, Shuixiang Deng, Feng Zhao, Yanqin Gao, Ye Gong
Format: Article
Language:English
Published: BMC 2022-04-01
Subjects:
Integrin αVβ5
Intracerebral hemorrhage
Irisin
AMPK
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-022-02438-6

Internet

https://doi.org/10.1186/s12974-022-02438-6

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