Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. We explored associations between CSF BACE1 ac...

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Bibliographic Details

Published in:	The Scientific World Journal
Main Authors:	Timo Grimmer, Panagiotis Alexopoulos, Amalia Tsolakidou, Liang-Hao Guo, Gjermund Henriksen, Behrooz H. Yousefi, Hans Förstl, Christian Sorg, Alexander Kurz, Alexander Drzezga, Robert Perneczky
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Online Access:	http://dx.doi.org/10.1100/2012/712048