Investigation of MSC potency metrics via integration of imaging modalities with lipidomic characterization

Summary: Mesenchymal stem/stromal cell (MSC) therapies have had limited success so far in clinical trials due in part to heterogeneity in immune-responsive phenotypes. Therefore, techniques to characterize these properties of MSCs are needed during biomanufacturing. Imaging cell shape, or morphology...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Priyanka Priyadarshani, Alexandria Van Grouw, Adrian Ross Liversage, Kejie Rui, Arina Nikitina, Kayvan Forouhesh Tehrani, Bhavay Aggarwal, Steven L. Stice, Saurabh Sinha, Melissa L. Kemp, Facundo M. Fernández, Luke J. Mortensen
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	CP: Metabolism CP: Immunology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724009082