Enhancing nanoparticle accumulation in two dimensional, three dimensional, and xenograft mouse cancer cell models in the presence of docetaxel

Abstract Recent clinical trials show docetaxel (DTX), given in conjunction with radiation therapy (RT) and androgen suppression, improves survival in high-risk prostate cancer. Addition of gold nanoparticles (GNPs) to this current DTX/RT protocol is expected to further improve therapeutic benefits r...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Kyle Bromma, Nancy Dos Santos, Ingrid Barta, Abraham Alexander, Wayne Beckham, Sunil Krishnan, Devika B. Chithrani
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Online Access:	https://doi.org/10.1038/s41598-022-17752-5