Topology-aware pathway analysis of spatial transcriptomics

Spatial transcriptomics (ST) has transformed genomics by mapping gene expression onto intact tissue architecture, uncovering intricate cellular interactions that bulk and single-cell RNA sequencing often overlook. Traditional ST workflows typically involve clustering spots, performing differential e...

Full description

Bibliographic Details
Published in:PeerJ
Main Authors: Siras Hakobyan, Maria Schmidt, Hans Binder, Arsen Arakelyan
Format: Article
Language:English
Published: PeerJ Inc. 2025-08-01
Subjects:
Online Access:https://peerj.com/articles/19729.pdf