Risk of potential hepatotoxicity from pirfenidone or nintedanib in patients with idiopathic pulmonary fibrosis: results of a retrospective analysis of a large insurance database in Taiwan

Background: A growing population of individuals diagnosed with idiopathic pulmonary fibrosis (IPF) are receiving treatment with nintedanib and pirfenidone. The aim of our study was to assess the incidence of drug-induced liver injury (DILI) associated with the use of pirfenidone and nintedanib in pa...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Kuang-Ming Liao, Chung-Yu Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	idiopathic pulmonary fibrosis nintedanib pirfenidone drug-induced liver injury hepatotoxicity
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1309712/full