Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines

<p>Abstract</p> <p>Introduction</p> <p>The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investigate its effect on the r...

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Bibliographic Details

Published in:	Radiation Oncology
Main Authors:	Kulozik Andreas E, Bischof Marc, Brons Stephan, Perez Ramon, Huber Peter E, Weber Klaus-J, Richter Karsten, Thiemann Markus, Oertel Susanne, Ehemann Volker, Debus Jürgen, Blattmann Claudia
Format:	Article
Language:	English
Published:	BMC 2011-09-01
Subjects:	Infantile sarcoma histone deacetylase inhibition heavy ion radiotherapy suberoylanilide hydroxamic acid SAHA
Online Access:	http://www.ro-journal.com/content/6/1/119