TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines

IntroductionT-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell survival and proliferation. In this study, we aimed to explore the effect of TI...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Mahnaz Rezaei, Mustafa Ghanadian, Behrooz Ghezelbash, Abolfazl Shokouhi, Alexandr V. Bazhin, Andrey A. Zamyatnin, Mazdak Ganjalikhani-Hakemi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	acute myeloid leukemia TIM-3 immunometabolism glucose metabolism lipid metabolism galectin-9
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267578/full