Impaired Contracture of 3D Collagen Constructs by Fibronectin-Deficient Murine Fibroblasts

Fibronectin (FN) is an extracellular matrix glycoprotein that is abundantly expressed by fibroblasts in contracting wounds, where it mediates cell adhesion, migration and proliferation. FN also efficiently binds to collagen. Therefore, we and others hypothesized that FN and its cellular receptor int...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Joël Beyeler, Christos Katsaros, Matthias Chiquet
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Subjects:	fibronectin alpha5-integrin collagen collagen contraction collagen contracture fibroblasts
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2019.00166/full