Endocannabinoid regulation of inward rectifier potassium (Kir) channels

The inward rectifier potassium channel Kir2.1 (KCNJ2) is an important regulator of resting membrane potential in both excitable and non-excitable cells. The functions of Kir2.1 channels are dependent on their lipid environment, including the availability of PI(4,5)P2, secondary anionic lipids, chole...

Full description

Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Sultan Mayar, Mariia Borbuliak, Andreas Zoumpoulakis, Tahar Bouceba, Madeleine M. Labonté, Ameneh Ahrari, Niveny Sinniah, Mina Memarpoor-Yazdi, Catherine Vénien-Bryan, D. Peter Tieleman, Nazzareno D’Avanzo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	Kir channel cannabinoids endocannabinoids ion channel molecular dynamics simulations
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1439767/full