Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation

Abstract Mammalian oocytes are notoriously prone to chromosome segregation errors leading to aneuploidy. The spindle provides the machinery for accurate chromosome segregation during cell division. Mammalian oocytes lack centrioles and, therefore, mouse meiotic spindle relies on the organization of...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Edgar J. Soto-Moreno, Nourhan N. Ali, Florian Küllmer, Veselin Nasufovic, Michaela Frolikova, Olga Tepla, Jaromir Masata, Dirk Trauner, Amanda A. Patterson, Hans-Dieter Arndt, Katerina Komrskova, Magdalena Zernicka-Goetz, David M. Glover, Ahmed Z. Balboula
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Online Access:	https://doi.org/10.1038/s41467-025-63586-w