Metabolic Imbalance Effect on Retinal Müller Glial Cells Reprogramming Capacity: Involvement of Histone Deacetylase SIRT6

Retinal Müller glial cells (MGs) are among the first to demonstrate metabolic changes during retinal disease and are a potential source of regenerative cells. In response to a harmful stimulus, they can dedifferentiate acquiring neural stem cells properties, proliferate and migrate to the damaged re...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	L Francisco Sanhueza Salas, Alfredo García-Venzor, Natalia Beltramone, Claudia Capurro, Debra Toiber, Dafne Magalí Silberman
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-11-01
Subjects:	retina müller cells metabolism reprogramming SIRT6
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.769723/full