Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

ABSTRACT The protein disulfide isomerase (PDI) family comprises 21 members that have oxidase, reductase, isomerase, and foldase activities essential for human health and disease. Protein disulfide isomerase A4 (PDIA4) is the largest member in this family. This family is pivotal in various human dise...

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Bibliographic Details

Published in:	Food Frontiers
Main Authors:	Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	cancer coagulation diabetes inhibitors protein disulfide isomerase (PDI) protein disulfide isomerase A4 (PDIA4)
Online Access:	https://doi.org/10.1002/fft2.70059