mastermind regulates niche ageing independently of the Notch pathway in the Drosophila ovary

Proper stem cell activity in tissues ensures the correct balance between proliferation and differentiation, thus allowing tissue homeostasis and repair. The Drosophila ovary develops well-defined niches that contain on average 2–4 germline stem cells (GSCs), whose maintenance depends on systemic sig...

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Bibliographic Details

Published in:	Open Biology
Main Authors:	María Lobo-Pecellín, Miriam Marín-Menguiano, Acaimo González-Reyes
Format:	Article
Language:	English
Published:	The Royal Society 2019-11-01
Subjects:	niche ageing mastermind reactive oxygen species de-cadherin hedgehog drosophila oogenesis
Online Access:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190127