The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity

Summary: Cytotoxic immunoglobulin G antibodies are an essential component of therapeutic approaches aimed at depleting self-reactive or malignant cells. More recent evidence suggests that the tissue in which the target cell resides influences the underlying molecular and cellular pathways responsibl...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Sina Gordan, Heike Albert, Heike Danzer, Anja Lux, Markus Biburger, Falk Nimmerjahn
Format: Article
Language:English
Published: Elsevier 2019-12-01
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314445