Epigenetic Factors in Pathogenesis of Retinoblastoma: DNA Methylation and Histone Acetylation

(Background) Retinoblastoma is the most common intraocular malignancy in childhood, primarily caused by mutations in the <i>RB1</i> gene. However, increasing evidence highlights the significant role of epigenetic mechanisms, particularly DNA methylation and histone acetylation, in tumor...

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Georgios Kiosis, Kanellos Skourtsidis, Despoina Ioannou, Vasilis-Spyridon Tseriotis, Konstantinos Stergiou, Fani Akritidou, Theodora Papamitsou, Maria Kourti, Sofia Karachrysafi
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	retinoblastoma epigenetics DNA methylation histone acetylation
Online Access:	https://www.mdpi.com/1467-3045/47/10/844