Diselenide-Bridged Doxorubicin Dimeric Prodrug: Synthesis and Redox-Triggered Drug Release

The diselenide bond has attracted intense interest in redox-responsive drug delivery systems (DDSs) in tumor chemotherapy, due to its higher sensitivity than the most investigated bond, namely the disulfide bond. Here, a diselenide-bridged doxorubicin dimeric prodrug (D-DOX<sub>SeSe</sub>...

Full description

Bibliographic Details
Published in:Molecules
Main Authors: Yanru Hu, Peng Liu
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Subjects:
tumor chemotherapy
dimeric prodrug
diselenide bond
redox triggered
combination of conjugations
doxorubicin
Online Access:https://www.mdpi.com/1420-3049/29/8/1709

Internet

https://www.mdpi.com/1420-3049/29/8/1709

Similar Items