Serum antibody profiling identifies vaccine-induced correlates of protection against aerosolized ricin toxin in rhesus macaques

Abstract Inhalation of the biothreat agent, ricin toxin (RT), provokes a localized inflammatory response associated with pulmonary congestion, edema, neutrophil infiltration, and severe acute respiratory distress. The extreme toxicity of RT is the result of the toxin’s B chain (RTB) promoting rapid...

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Bibliographic Details

Published in:	npj Vaccines
Main Authors:	Chad J. Roy, Dylan Ehrbar, Greta Van Slyke, Jennifer Doering, Peter J. Didier, Lara Doyle-Meyers, Oreola Donini, Ellen S. Vitetta, Nicholas J. Mantis
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-12-01
Online Access:	https://doi.org/10.1038/s41541-022-00582-x