Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment.

BACKGROUND:Although ethanol exerts widespread action in the brain, only recently has progress been made in understanding the specific events occurring at the synapse during ethanol exposure. Mice deficient in the calcium-stimulated adenylyl cyclases, AC1 and AC8 (DKO), demonstrate increased sedation...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Alana C Conti, James W Maas, Krista L Moulder, Xiaoping Jiang, Bhumy A Dave, Steven Mennerick, Louis J Muglia
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-05-01
Online Access:	http://europepmc.org/articles/PMC2682654?pdf=render