Exosomal miR92a Promotes Cytarabine Resistance in Myelodysplastic Syndromes by Activating Wnt/β-catenin Signal Pathway

Cytarabine (Ara-C) has been one of the frontline therapies for clonal hematopoietic stem cell disorders, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), but Ara-C resistance often occurs and leads to treatment failure. Exosomal microRNAs (miRNAs, miRs) as small noncoding RNA...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Hongjiao Li, Chenglian Xie, Yurong Lu, Kaijing Chang, Feng Guan, Xiang Li
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	MDS/AML exosomal miR92a Ara-C resistance PTEN Wnt/β-catenin
Online Access:	https://www.mdpi.com/2218-273X/12/10/1448