Mechanical Deformation Mechanisms and Properties of Prion Fibrils Probed by Atomistic Simulations

Abstract Prion fibrils, which are a hallmark for neurodegenerative diseases, have recently been found to exhibit the structural diversity that governs disease pathology. Despite our recent finding concerning the role of the disease-specific structure of prion fibrils in determining their elastic pro...

Full description

Bibliographic Details

Published in:	Nanoscale Research Letters
Main Authors:	Bumjoon Choi, Taehee Kim, Eue Soo Ahn, Sang Woo Lee, Kilho Eom
Format:	Article
Language:	English
Published:	SpringerOpen 2017-03-01
Subjects:	Prion fibril Mechanical deformation mechanism Fracture property Atomistic simulation
Online Access:	http://link.springer.com/article/10.1186/s11671-017-1966-3