Ectonucleotidases in Intestinal and Hepatic Inflammation
Purinergic signaling modulates systemic and local inflammatory responses. Extracellular nucleotides, including eATP, promote inflammation, at least in part via the inflammasome upon engagement of P2 purinergic receptors. In contrast, adenosine generated during eATP phosphohydrolysis by ectonucleotid...
| Published in: | Frontiers in Immunology |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-03-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.00507/full |