Targeting FLT3 Mutations in Acute Myeloid Leukemia

The FMS-like tyrosine kinase 3 (FLT3) pathway has an important role in cellular proliferation, survival, and differentiation. Acute myeloid leukemia (AML) patients with mutated FLT3 have a large disease burden at presentation and a dismal prognosis. A number of FLT3 inhibitors have been developed ov...

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Bibliographic Details

Published in:	Cells
Main Authors:	Riad El Fakih, Walid Rasheed, Yousef Hawsawi, Maamoun Alsermani, Mona Hassanein
Format:	Article
Language:	English
Published:	MDPI AG 2018-01-01
Subjects:	FMS-like tyrosine kinase 3 acute myeloid leukemia Midostaurine
Online Access:	http://www.mdpi.com/2073-4409/7/1/4