Development of a colloidal gold immunochromatographic assay utilizing dual-antibody sandwich method for detecting Orientia tsutsugamushi

A colloidal gold immunochromatographic assay (ICA) based on a dual-antibody sandwich method was developed for the rapid and convenient detection of Orientia tsutsugamushi (O. tsutsugamushi) antigens in the early stages of infection. Monoclonal antibodies designed as 5B3 targeting the conserved regio...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Qingyu Lu, Shiyin Yu, Sibo Wang, Min Cao, Liuxin Li, Miao Xin, Weilong Tan, Yong Qi, Yichen Lu, Xiaohui Xiong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Subjects:	O. tsutsugamushi monoclonal antibody polyclonal antibody immunochromatography colloidal gold
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1521015/full