Dual Action of Memantine in Alzheimer Disease: A Hypothesis

Objective: In this study, we proposed a hypothesis to explain the mechanisms of memantine action in treating Alzheimer disease (AD). Memantine may reduce the expression of amyloid precursor protein and tau protein, as well as acting as an antagonist of N-methyl-d-aspartate receptors in the brain. Re...

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Bibliographic Details
Published in:Taiwanese Journal of Obstetrics & Gynecology
Main Authors: Tzong-Yuan Wu, Chih-Ping Chen
Format: Article
Language:English
Published: Elsevier 2009-09-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S102845590960303X