An investigation of neuromelanin distribution in substantia nigra and locus coeruleus in patients with Parkinson’s disease using neuromelanin-sensitive MRI

Abstract Loss of neuromelanin in the midbrain is known in Parkinson’s disease(PD), which can now be directly detected by neuromelanin-sensitive MRI(NM-MRI). This case-control study was to investigate the distribution of neuromelanin in the substantia nigra(SN) and the locus coeruleus(LC) using NM-MR...

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Bibliographic Details

Published in:	BMC Neurology
Main Authors:	Qiang Liu, Pan Wang, Chenghe Liu, Feng Xue, Qian Wang, Yuqing Chen, Ruihua Hou, Teng Chen
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Subjects:	Parkinson’s Disease Neuromelanin Neuromelanin-sensitive MRI Substantia Nigra Locus Coeruleus
Online Access:	https://doi.org/10.1186/s12883-023-03350-z