In-vivo thrombolytic efficacy of RGD modified protein-polymer conjugated urokinase nanogels

It has been shown that an arginine-glycine-aspartic acid (RGD) modified pH-triggered delivery system for the urokinase-type plasminogen activator (uPA) is resistant to enzymatic degradation and improves thrombolytic ability in vitro. Herein, we aimed to compare the thrombolytic efficacies of uPA-oxi...

詳細記述

書誌詳細

出版年:	Polymer Testing
主要な著者:	Xia Liu, Ling-Li Jin, Ling-Ling Zhao, Ya-Chao Wang, Liping Zhang, Zheng-Zheng Huang, Hai-Qiang Jin, Jun-Ying Liu, Zhen-Jiang Liang, Xuan Liu, Hui Tan, Li-Jie Ren
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2021-12-01
主題:	RGD pH-triggered delivery Targeted thrombolysis Stroke Blood-brain barrier
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S0142941821003378